Bio Perfected, L-Ergothioneine

EGT suppresses the expression of MMP-1 that causes collagen degradation and premature skin aging

EGT increases type-1 procollagen expression in UVA-exposed HSF cells.

EGT prevents changes to gene expressions in fibroblasts in the derma compartment

EGT inhibits the AP-1 pathway and activates Nrf2-mediated antioxidant genes

Enables DNA repair in keratinocytes exposed to UV radiation]

Inhibits DNA fragmentation and LDH leakage caused by UVA-induced cytotoxicity

Increases DNA synthesis in UVA-irradiated cells

Prevents DNA halogenation and pre-mature apoptosis in human keratinocytes